基本情況
姓名：李蘇華
性别：男
出生年月：1983-05
籍貫：江蘇姜堰 （江西德安人）
職位：教授，博士生導師
聯系方式
電話：暫未填寫
傳真：暫未填寫
郵箱：lisuhua5@mail.sysu.edu.cn
通訊地址：廣州市番禺區大學城外環東路132号中大東校區化學材料大樓A1006
郵編：510006
個人網站：暫未填寫
教育經曆
2007.09–2012.07 中國科學院上海有機化學研究所，有機化學博士 導師：麻生明 院士
2002.09–2006.06 南京大學 化學學士學位
工作經曆
2017.07–至今 太阳集团1088vip，教授，博士生導師
2014.07–2017.06 The Scripps Research Institute 博士後 合作導師：K. Barry Sharpless教授
2012.08–2014.07 The Scripps Research Institute 博士後 合作導師：Jin-Quan Yu教授
2006.08–2007.09 康化（上海）新藥研發有限公司
講授課程
《有機合成化學》（課程負責人）
《金屬有機化學》
《現代化學研究方法與技術》
科研方向
通過發展新試劑和新方法來探索經濟、高效的有機合成反應，發展基礎化學品的綠色合成新路線，實現資源化合物的高效轉化，尋求在能源、環境、材料以及生物中的應用。
課題組長期招聘博士後。我們熱誠歡迎碩士和博士研究生加入本課題組，同時歡迎本科生利用課餘時間來本組短期或長期交流學習
科研項目
太阳集团app首页“百人計劃”啟動經費
獲獎情況
. 黃文洪有機化學獎教金，2021
. 2021 Horizon Prize: Robert Robinson Award in Synthetic Chemistry (Team awards for the development of multidimensional click chemistry), RSC, 2021
. 2011年度麻生明小組“研究貢獻獎”, 2012
. 布勞恩獎學金, 布勞恩惰性氣體系統有限公司, 2011
. 中國科學院院長優秀獎, 2011
論著一覽
47. Shun Liu, Qidong Zhang, Ji Ma, Xiankuan Huo, Lingbo Ji, Baojiang He, Guobi Chai, Qingzhao Shi, Jian Mao, Hui Xi, Wu Fan,* and Suhua Li*
Highly Regio- and Stereoselective Dehydration of Allylic Alcohols to Conjugated Dienes via 1,4-syn-Elimination with H2 Evolution
46. Zhiyuan Peng, Shoujun Sun, Meng-Meng Zheng, Yangyang Li, Xixi Li, Suhua Li, Xiao-Song Xue,* Jiajia Dong,* Bing Gao*
Enantioselective sulfur(VI) fluoride exchange reaction of iminosulfur oxydifluorides
45. Shouzhi Zhang, Wu Fan,* Suhua Li*
Synthesis and Applications of Trifluoromethylphosphines
Eur. J. Org. Chem. 2024, 27, e202301169.
44. Bingyin Meng,# Luyao Liu,# Xiaotong Shen, Wu Fan,*, and Suhua Li*
Pyridine N-Oxide-Promoted Cobalt-Catalyzed Dioxygen-Mediated Methane Oxidation
43. Deqian Peng,# Shouzhi Zhang,# Wu Fan, Yuan Wen, Suhua Li*
Zn-Mediated Scalable Synthesis of Trifluoromethylphosphines from Phosphine Chlorides and CF3Br
Org. Lett. 2023, 25, 3892−3897. (Highlighted in Organic Chemistry Portal)
42. Yuan Wen, Ruifang Nie, Bo Li, Suhua Li*
Ligand-Promoted Bifunctional Cobalt-Catalyzed Carbonylation-Polymerization of Epoxides: One Step to Polyhydroxyalkanoates
41. Luyao Liu, Wu Fan, Suhua Li*
NaCl-Promoted Cobalt-Catalyzed Dioxygen-Mediated Methane Oxidation to Methylene Bis(trifluoroacetate) with a Dramatic Salt Effect
40. Bo Li, Shihao Liu, Wu Fan, Xiaotong Shen, Jing Xu, Suhua Li*
Ligand enabled none-oxidative decarbonylation of aliphatic aldehydes
Chin. Chem. Lett. 2023, 34, 108027.
39. Licheng Sang, Weiyi Yang, Shuang Gao, Suhua Li, Jian Ku Shang, Qi Li,*
Photocatalytic activity of polyacrylonitrile under simulated solar illumination
Chem. Eng. J., 2022, 434, 134697.
38. Liangzhi Pang, Qilin Sun, Zhan Huang, Suhua Li,* Qiankun Li*
Cobalt–Tertiary Amine Mediated Peroxy-trifluoromethylation and -halodifluoromethylation of Alkenes with CF2XBr (X = F, Cl, Br) and tert-Butyl Hydroperoxide
37. Qilin Sun, Liangzhi Pang, Shuxian Mao, Wu Fan, Yuyi Zhou, Jing Xu, Suhua Li* Qiankun Li*
Cobalt-Catalyzed Hydroxyperfluoroalkylation of Alkenes with Perfluoroalkyl Bromides and Atmospheric Oxygen
36. Deqian Peng, Wu Fan, Xueqi Zhao, Wei Chen, Yuan Wen, Li Zhang, Suhua Li*
Zinc-Brønsted Acid Mediated Practical Hydrotrifluoromethylation of Alkenes with CF3Br
Org. Chem. Front., 2021, 8, 6356.
35. Suhua Li,* Gencheng Li, Bing Gao, Sidharam P. Pujari,Xiaoyan Chen, Hyunseok Kim, Feng Zhou, Liana M. Klivansky, Yi Liu, Hafedh Driss, Dong-Dong Liang, Jianmei Lu, Peng Wu,* Han Zuilhof,* John Moses,* K. Barry Sharpless,*
SuFExable polymers with helical structures derived from thionyl tetrafluoride
34. Luyao Liu, Wu Fan, Wei Chen, Xiaoyan Chen, Suhua Li*
KF-Promoted Copper-Catalyzed Highly Efficient and Selective Oxidation of Methane and other Alkanes with Dramatic Additive Effect
Catal. Sci. Technol., 2021, 11, 4962.
33. Qiankun Li, Wu Fan, Deqian Peng, Bingyin Meng, Shaohan Wang, Rui Huang, Shihao Liu, and Suhua Li*
Cobalt−Tertiary-Amine-Mediated Hydroxytrifluoromethylation of Alkenes with CF3Br and Atmospheric Oxygen
32. Gabriel J. Brighty#, Rachel C. Botham#, Suhua Li#, Luke Nelson, David E. Mortenson, Gencheng Li, Christophe Morisseau, Hua Wang, Bruce D. Hammock, K. Barry Sharpless, Jeffery W. Kelly
Using sulfuramidimidoyl fluorides that undergo sulfur(VI) fluoride exchange for inverse drug discovery
31. A. S. Barrow, C. J. Smedley, Q. Zheng, S. Li, J. Dong, J. E. Moses*
The growing applications of SuFEx click chemistry
Chem. Soc. Rev. 2019, 48, 4731.
30. Feng Liu#, Hua Wang#, Suhua Li, Grant A. L. Bare, Xuemin Chen, Chu Wang, John E. Moses, Peng Wu, K. Barry Sharpless*
Biocompatible SuFEx Click Chemistry: Thionyl Tetrafluoride (SOF4)-Derived Connective Hubs for Bioconjugation to DNA and Proteins
Angew. Chem. Int. Ed. 2019, 58, 8029.
29. Digvijay Gahtory, Rickdeb Sen, Sidharam Pujari, Suhua Li, Qinheng Zheng, John E. Moses,* K. Barry Sharpless,* Han Zuilhof*
Quantitative and Orthogonal Formation and Reactivity of SuFEx Platforms
Chem. Eur. J. 2018, 24, 10550.
28. Zilei Liu#, Jie Li#, Suhua Li#, Gencheng Li, K. Barry Sharpless, Peng Wu*,
SuFEx Click Chemistry Enabled Late-Stage Drug Functionalization
J. Am. Chem. Soc., 2018, 140, 2919.
27. Bing Gao, Suhua Li, Peng Wu, John E. Moses, K. Barry Sharpless*
SuFEx Chemistry of Thionyl Tetrafluoride (SOF4) with Organolithium Nucleophiles: Synthesis of Sulfonimidoyl Fluorides, Sulfoximines, Sulfonimidamides, and Sulfonimidates
Angew. Chem. Int. Ed. 2018, 57, 1939.
26. David E. Mortenson, Gabriel J. Brighty, Lars Plate, Grant Bare, Wentao Chen, Suhua Li, Hua Wang, Benjamin F. Cravatt, Stefano Forli, Evan T. Powers, K. Barry Sharpless*Ian A. Wilson*, Jeffery W. Kelly*
“Inverse Drug Discovery” Strategy To Identify Proteins That Are Targeted by Latent Electrophiles As Exemplified by Aryl Fluorosulfates
J. Am. Chem. Soc. 2018, 140, 200.
25. Wan Jung Kim, Keith Korthals, Suhua Li, Christine Le, Jaroslaw Kalisiak, K. Barry Sharpless, Valery V. Fokin, Yukiko Miyamoto, Lars Eckmann*
Click chemistry-facilitated structural diversification of nitrothiazoles, nitrofurans and nitropyrroles enhances antimicrobial activity against Giardia lamblia
Antimicrob. Agents Chemother. 2017, 61, e02397-16.
24. Bukeyan Miao, Yangguangyan Zheng, Penglin Wu, Suhua Li, Shengming Ma*
Bis(cycloocta-1,5-diene)nickel-Catalyzed Carbon Dioxide Fixation for Stereoselective Synthesis of 3-Alkylidene-2-indolinones
Adv. Synth. Catal. 2017, 359, 1691.
23. Suhua Li, Peng Wu, John E. Moses, K. Barry Sharpless*
Multidimensional SuFEx Click Chemistry: Sequential Sulfur(VI) Fluoride Exchange Connections of Diverse Modules Launched From An SOF4 Hub
Angew. Chem. Int. Ed. 2017, 56, 2903. (VIP paper, highlighted in C&E News, 2017, 95, 10; Chemistry World)
22. Haiyan Fu, Peng-Xiang Shen, Jian He, Fanglin Zhang, Suhua Li, Peng Wang, Tao Liu, Jin-Quan Yu*
Ligand-Enabled Alkynylation of C(sp3)-H Bonds with Pd(II) Catalysts
Angew. Chem. Int. Ed. 2017, 56, 1873.
21. Wentao Chen#, Jiajia Dong#, Lars Plate#, David E. Mortenson, Gabriel J. Brighty, Suhua Li, Yu Liu, Andrea Galmozzi, Peter S. Lee, Jonathan J. Hulce, Benjamin F. Cravatt, Enrique Saez, Evan T. Powers, Ian A. Wilson, K. Barry Sharpless*, Jeffery W. Kelly*
Arylfluorosulfates Inactivate Intracellular Lipid Binding Protein(s) through Chemoselective SuFEx Reaction with a Binding Site Tyr Residue
J. Am. Chem. Soc. 2016, 138, 7353.
20. Bukeyan Miao, Suhua Li, Gen Li and Shengming Ma*
Cyclic Anti-Azacarboxylation of 2‑Alkynylanilines with Carbon Dioxide
Org. Lett. 2016, 18, 2556. (Highlighted in Synfacts, 2016, 12, 890.)
19. Suhua Li, Ru-Yi Zhu, Kai-Jiong Xiao and Jin-Quan Yu*
Ligand-Enabled Arylation of γ-C-H Bonds
Angew. Chem. Int. Ed. 2016, 55, 4317.
18. Enxuan Zhang*, Jiaze Tang, Suhua Li, Peng Wu, John E. Moses and K. Barry Sharpless*
Chemoselective Synthesis of Polysubstituted Pyridines From Heteroaryl Fluorosulfates
Chem. Eur. J. 2016, 22, 5692-5697. (Highlighted in Synfacts, 2016, 12, 617.)
17. Wentao Chen#, Jiajia Dong#, Suhua Li, Yu Liu, Yujia Wang, Leonard Yoon, Peng Wu, K. Barry Sharpless*, Jeffery W. Kelly*
Synthesis of Sulfotyrosine-Containing Peptides by Incorporating Fluorosulfated Tyrosine Using an Fmoc-Based Solid-Phase Strategy
Angew. Chem. Int. Ed. 2016, 55, 1835.
16. Ru-Yi Zhu, Keita Tanaka, Gen-Cheng Li, Jian He, Hai-Yan Fu, Suhua Li and Jin-Quan Yu*
Ligand-Enabled Stereoselective β-C(sp3)–H Fluorination: Synthesis of Unnatural Enantiopure anti-β-Fluoro-α-amino Acids
J. Am. Chem. Soc. 2015, 137, 7067.
15. Xiao-Chen Wang, Wei Gong, Li-Zhen Fang, Ru-Yi Zhu, Suhua Li, Keary M. Engle and Jin-Quan Yu*
Ligand-enabled meta-C–H activation using a transient mediator
14. Gang Chen, Toshihiko Shigenari, Pankaj Jain, Zhipeng Zhang, Zhong Jin, Jian He, Suhua Li, Claudio Mapelli, Michael M. Miller, Michael A. Poss, Paul M. Scola, Kap-Sun Yeung and Jin-Quan Yu*
Ligand-Enabled beta-C–H Arylation of alpha-Amino Acids Using a Simple and Practical Auxiliary
J. Am. Chem. Soc. 2015, 137, 3338.
13. Suhua Li, Gang Chen, Chen-Guo Feng, Wei Gong and Jin-Quan Yu*
Ligand-Enabled γ-C–H Olefination and Carbonylation: Construction of β-Quaternary Carbon Centers
J. Am. Chem. Soc. 2014, 136, 5267. (Highlighted in Organic Chemistry Portal, 2015, Jan 26th)
12. Jian He#, Suhua Li#, Youqian Deng, Haiyan Fu, Brian N. Laforteza, Jillian E. Spangler, Anna Homs and Jin-Quan Yu*
Ligand-Controlled C(sp3)–H Arylation and Olefination in Synthesis of Unnatural Chiral α–Amino Acids,
Science, 2014, 343, 1216. (Highlighted in C&EN News, 2014, 92, 5.)
11. Chen-Guo Feng, Mengchun Ye, Kai-Jiong Xiao, Suhua Li and Jin-Quan Yu*
Pd(II)-Catalyzed Phosphorylation of Aryl C–H Bonds
J. Am. Chem. Soc. 2013, 135, 9322.
10. Suhua Li, Juntao Ye, Weiming Yuan and Shengming Ma*
Highly Regioselective Three-component Palladium-Catalyzed Synthesis of 5-Vinyloxazolidin-2-one from 2,3-Allenyl Amines, Organic Iodides and Carbon Dioxide
9. Juntao Ye, Suhua Li and Shengming Ma*
Gorlos-phos: Addressing the Stereoselectivity in Palladium-catalyzed Exo-mode Cyclization of Allenes with a Nucleophilic Functionality
Org. Biomol. Chem. 2013, 11, 5370.
8. Suhua Li, Bukeyan, Miao, Weiming Yuan and Shengming Ma*
Carbometalation–Carboxylation of 2,3-Allenols with Carbon Dioxide: A Dramatic Effect of Halide Anion
Org. Lett., 2013, 15, 977. (Highlighted in Organic Chemistry Portal, Abstracts: http://www.organic-chemistry.org/abstracts/lit3/945.shtm)
7. Juntao Ye, Suhua Li and Shengming Ma*
Palladium-Catalyzed Cyclization Reactions of 2,3-Allenyl Amines with Propargylic Carbonates
6. Suhua Li and Shengming Ma*
Quadri-Synergetic Effect for Highly Effective Carbon Dioxide Fixation and Its Application to Indoloquinolinone
Adv. Synth. Catal. 2012, 354, 2387.
5. Juntao Ye, Suhua Li, Bo Chen, Wu Fan, Jingqiang Kuang, Jinxian Liu, Yu Liu, Bukeyan Miao, Bao Wan, Yuli Wang, Xi Xie, Qiong Yu, Weiming Yuan and Shengming, Ma*
Catalytic Asymmetric Synthesis of Optically Active Allenes from Terminal Alkynes
4. Suhua Li and Shengming Ma*
CO2-Activation for γ-Butyrolactones and its Application in the Total Synthesis of (±)-Heteroplexisolide E
3. Suhua Li and Shengming Ma*
Highly Selective Nickel-Catalyzed Methyl-Carboxylation of Homopropargylic Alcohols for α-Alkylidene-γ-butyrolactones
Org. Lett. 2011, 13, 6046. (Highlighted in Synfacts, 2012, 8, 196.)
2. Suhua Li, Weiming Yuan and Shengming Ma*
Highly Regio- and Stereoselective Three-Component Nickel-Catalyzed syn-Hydrocarboxylation of Alkynes with Diethyl Zinc and Carbon Dioxide
Angew. Chem. Int. Ed. 2011, 50, 2578. (Highlighted in Nature China doi: 10.1038/nchina.2011.13; Angew. Chem. Int. Ed. 2011, 50, 6210.)
1. Shengming Ma*, Jinxian Liu, Suhua Li, Bo Chen, Jiajia Cheng, Jinqiang Kuan, Yu Liu, Baoqiang Wan, Yuli Wang, Juntao Ye, Qiong Yu, Weiming Yuan and Shichao Yu
Development of a General and Practical Iron Nitrate/TEMPO Catalyzed Aerobic Oxidation of Alcohols to Aldehydes/Ketones: Catalysis with Table Salt
Adv. Synth. Catal. 2011, 353, 1005.
