基本情況
姓名：陳國勝
性别：男
出生年月：1990-05
籍貫：廣東台山
職位：太阳集团1088vip副教授、博士生導師
聯系方式
郵箱：chengsh39@mail.sysu.edu.cn
通訊地址：廣東省廣州市番禺區小谷圍街道太阳集团app首页化學材料綜合大樓A460
郵編：510006
教育經曆
2013.09-2018.06：太阳集团app首页物理化學專業，博士（導師：歐陽鋼鋒教授）
2009.09-2013.06：太阳集团app首页應用化學專業，學士
工作經曆
2021.02-現在：太阳集团1088vip，副教授
2018.12-2020.12：太阳集团1088vip，博士後
講授課程
本科生：儀器分析教程；大學化學實驗（1）；儀器分析實驗；綜合化學實驗（II）
研究生：現代化學研究技術與技能訓練
科研方向
面向分析測量和環境污染控制的新型功能材料的基礎及應用研究，包括酶-多孔晶态雜化框架設計、生物傳感及标志物分析新方法和環境催化新技術等方面的研究工作，以第一/通訊作者身份在Nat. Protoc.、Sci. Adv.、Nat. Commun.、Chem、JACS、Angew. Chem.、Matter、CCS Chem等期刊發表SCI論文45篇。
科研項目
主持的部分科研項目：
1. 中組部青年拔尖人才（2024-12至2027-11，項目負責人）
2. 廣東省自然科學基金傑出青年基金項目（2024-01至2027-12，項目負責人）
3. 國家自然科學基金面上項目（2022-01至2025-12，項目負責人）
4. 國家自然科學基金青年項目（2020-01至2022-12，項目負責人）
5. 中國博士後創新人才支持計劃（2019-09至2021-08，項目負責人）
6. 中國博士後基金面上項目（2019-05至2021-05，項目負責人）
7. 廣東省自然科學基金面上項目（2019-10至2022-09，項目負責人）
8. 太阳集团app首页青年拔尖人才計劃（2023-01至2024-12，項目負責人）
9. 太阳集团app首页青年教師培育項目（2019-01至2021-12，項目負責人）
獎勵情況
1. 入選國家級高層次青年人才
2. 廣東省傑出青年基金
3. 2022年中國分析測試協會科學技術獎CAIA獎特等獎（第二完成人）
4. 入選博新人才支持計劃
5. “微瑞杯”第二屆全國大學生化學實驗創新設計競賽總決賽特等獎（指導老師）
6. 入選由英國分析化學家網評選的2022年度全球40位40歲以下精英分析化學家名單
7. 入選2023和2024年度全球前2%頂尖科學家榜單
代表性論文
(1) Huang, Siming; Chen,Guosheng*; Ouyang, Gangfeng*. Confining enzymes in porous organicframeworks: from synthetic strategy and characterization to healthcareapplications. Chem.Soc. Rev. 2022, 51, 6824-6863 (ESI highly cited paper).
(2) Chen,Guosheng*; Huang, Siming; Ma, Xiaomin; He, Rongwei; Ouyang, Gangfeng*.Encapsulating and stabilizing enzymes using hydrogen-bonded organic frameworks.Nat. Protoc. 2023, 18, 2032–2050 (ESI highly cited paper).
(3) Tong, Linjing;Huang, Siming; Shen, Yujian; Liu, Suya; Ma, Xiaomin; Zhu, Fang; Chen, Guosheng*; Ouyang,Gangfeng. Atomically unveiling the structure-activity relationship ofbiomacromolecule-metal-organic frameworks symbiotic crystal. Nat. Commun. 2022, 13, 951 (ESI highly cited paper).
(4) Chen, Guosheng*; Tong, Linjing;Huang, Siming; Huang, Shuyao; Zhu, Fang; Ouyang, Gangfeng*. Hydrogen-bondedorganic framework biomimetic entrapment allowing non-native biocatalyticactivity in enzyme. Nat. Commun. 2022, 13, 4816 (Featured Articlein chemical biology).
(5) Huang, Wei;Yuan, Haitao; Yang, Huangsheng; Ma, Xiaomin; Huang, Shuyao; Zhang, Hongjie;Huang, Siming; Chen, Guosheng*;and Ouyang, Gangfeng*.Green synthesis of stable hybrid biocatalyst using ahydrogen-bonded, π-π-stacking supramolecular assembly for electrochemicalimmunosensor. Nat.Commun. 2023, 14, 3644 (Featured Article in chemical biology).
(6) Jiang, Ruifen#; Luo, Gan#; Chen, Guosheng*; Lin, Yuhong; Tong, Linjing; Huang, Anlian; Zheng, Yang; Shen, Yong*; Huang, Siming; Ouyang, Gangfeng*. Boosting the photocatalytic decontamination efficiency using a supramolecular photo-enzyme ensemble. Science Advances, 2024, 10, eadp1796.
(7) Tong, Linjing; Gong, Zeyu; Wang, Yidong; Luo, Jiaxuan; Huang, Siming; Gao, Rui; Chen, Guosheng*; Ouyang, Gangfeng. Atomically Precise Regulation of the N-Heterocyclic Microenvironment in Triazine Covalent Organic Frameworks for Coenzyme Photocatalytic Regeneration. J. Am. Chem. Soc. 2024, 146, 21025-21033.
(8) Guo, Lihong, He, Rongwei, Chen, Guosheng*, Yang, Huangsheng, Kou, Xiaoxue, Huang, Wei, Gao, Rui*, Huang, Shuyao*, Huang, Siming*, Zhu, Fang, Ouyang, Gangfeng*. A Synergetic Pore Compartmentalization and Hydrophobization Strategy for Synchronously Boosting the Stability and Activity of Enzyme. J. Am. Chem. Soc. 2024, 146, 17189-17200.
(9) Huang, Siming*; Li, Jiansheng; Lin, Yuhong; Tong,Linjing; Zhong, Ningyi; Huang, Anlian; Ma, Xiaomin; Huang, Shuyao; Yi, Wei; Shen, Yong*; Chen, Guosheng*; Ouyang, Gangfeng*. Hydrogen-bonded supramolecular nanotrap enabling thein-terfacial activation of hosted enzyme. J. Am. Chem. Soc. 2024, 146, 3, 1967–1976 (Selected as Cover Paper).
(10) Chen, Guosheng#; Huang, Siming#; Shen, Yong; Kou, Xiaoxue; Ma, Xiaomin; Huang, Shuyao; Tong, Qing; Ma, Kaili; Chen, Wen; Wang, Peiyi; Shen, Jun; Zhu,Fang; Ouyang, Gangfeng*. Proteins-directed, hydrogen-bonded biohybrid framework. Chem 2021, 7, 2722-2742.
(11) Gao, Rui+; Kou, Xiaoxue+; Tong, Linjing; Li, Zhi-Wei; Shen, Yujian; He, Rongwei; Guo, Lihong; Wang, Hao; Ma, Xiaomin; Huang, Siming; Chen, Guosheng*; and Ouyang, Gangfeng. Ionic Liquid-Mediated Dynamic Polymerization for Facile Aqueous-Phase Synthesis of Enzyme-Covalent Organic Framework Biocatalysts. Angew. Chem. Int. Ed. 2024, e202319876.
(12) Tong, Linjing; Lin, Yuhong; Kou, Xiaoxue; Shen, Yujian;Shen, Yong*; Huang, Siming*; Zhu, Fang; Chen, Guosheng*; Ouyang, Gangfeng. Pore-Environment-Dependent Photoresponsive Oxidase-like Activity in Hydrogen-Bonded Organic Frameworks. Angew. Chem.Int. Ed. 2023, 62, e202218661(VIP paper).
(13) Tang, Zhuopeng#; Li, Xinyi#; Tong, Linjing; Yang, Huangsheng; Wu,Jiayi; Zhang, Xiliu; Song,Ting*; Huang, Siming*; Zhu, Fang; Chen, Guosheng*; Ouyang, Gangfeng. A Biocatalytic Cascade in an UltrastableMesoporous Hydrogen Bonded Organic Framework for Point-of-Care Biosensing. Angew. Chem.Int. Ed. 2021, 60, 23608-23613(Hot paper).
(14) Chen, Guosheng#; Huang, Siming#; Kou, Xiaoxue; Zhu, Fang; Ouyang, Gangfeng*. Embedding Functional Biomacromolecules within Peptide-Directed Metal-Organic Framework (MOF) Nanoarchitectures Enables Activity Enhancement. Angew. Chem.Int. Ed. 2020, 59, 13947-13954 (VIP paper).
(15) Chen, Guosheng; Kou, Xiaoxue; Huang, Siming; Tong, Linjing; Shen, Yujian;Zhu, Wangshu; Zhu, Fang; Ouyang, Gangfeng*. Modulatingthe Biofunctionality of Metal-Organic Framework-Encapsulated Enzymes through Controllable Embedding Patterns. Angew. Chem. Int. Ed. 2020, 59, 2867-2874 (ESIhighly cited paper).
(16) Huang, Siming; Kou, Xiaoxue; Shen, Jun; Chen, Guosheng*; Ouyang,Gangfeng*. "Armor-Plating" Enzymes with Metal-Organic Frameworks (MOFs). Angew. Chem. Int. Ed. 2020, 59,8786-8798 (ESI highly cited paper).
(17) Chen,Guosheng; Huang, Siming; Kou, Xiaoxue; Wei, Songbo; Huang, Shuyao;Jiang, Shuqi; Shen, Jun; Zhu, Fang; Ouyang, Gangfeng*. A Convenient and Versatile Amino-Acid-Boosted Biomimetic Strategy for the Nondestructive Encapsulation of Biomacromolecules within Metal–Organic Frameworks. Angew. Chem.Int. Ed. 2019, 58, 1463 –1467(ESI highly cited paper).
(18) Huang, Anlian; Yang, Huangsheng; Huang, Siming; Chen, Guosheng*; Ouyang, Gangfeng*. Hydrogen-bonded supramolecular crystal: A manual exoskeleton forbioentity. Matter 2023, 6, 2635–2646.
(19) Kou, Xiaoxue; Lin, Yuhong; Shen, Yong; Tong,Linjing; Gao, Rui; Liu, Suya; Huang, Siming; Zhu, Fang; Chen, Guosheng*; Gangfeng Ouyang. Biomimetic phosphohydrolase nanozyme based on defect-engineered metal-organic framework. CCS Chem. 2024, 6, 1821-1835.
(20) Huang, Wei#; Yuan, Haitao#; Yang, Huangsheng; Tong, Linjing; Gao, Rui; Kou, Xiaoxue; Wang, Jigang*; Ma, Xiaomin; Huang, Siming*; Zhu, Fang; Chen, Guosheng*; Ouyang, Gangfeng. Photodynamic Hydrogen-Bonded Biohybrid Framework: A Photobiocatalytic Cascade Nanoreactor for Accelerating DiabeticWound Therapy. JACS Au 2022, 2, 2048-2058.
(21) Huang, Anlian; Tong, Linjing; Kou, Xiaoxue; Gao, Rui;Li, Zhi-Wei*; Huang, Siming*; Zhu, Fang; Chen, Guosheng*; Ouyang, Gangfeng. Structural and Functional Insights intothe Biomineralized Zeolite Imidazole Frameworks. ACS Nano 2023, 17, 24130−24140.
(22) Chen, Guosheng; Kou, Xiaoxue; Huang, Siming; Huang, Shuyao; Zhang, Rui; Liu, Chao; Shen, Jun; Zhu, Fang*; Ouyang, Gangfeng*. Allochroic-Graphene Oxide Linked 3D Oriented Surface Imprinting Strategy for Glycoproteins Assays. Adv. Funct. Mater. 2018,1804129.
(23) Chen, Guosheng; Fang, Xu’an; Chen, Qing; Zhang, Jin’ge; Zhong, Zhensong; Xu,Jianqiao; Zhu, Fang*; Ouyang, Gangfeng*. Boronic Acid Decorated Defective Metal–Organic Framework Nanoreactors for High-Efficiency Carbohydrates Separation and Labeling. Adv. Funct. Mater. 2017, 27, 1702126.
(24) Chen, Guosheng; Qiu, Junlang; Xu, Jianqiao; Fang, Xu’an; Liu, Yan; Liu,Shuqin; Wei, Songbo; Jiang, Ruifen; Zeng, Feng; Luan, Tiangang; Zhu, Fang*; Ouyang, Gangfeng*. A novel probe based on phenylboronic acid functionalized carbon nanotubes for ultrasensitive carbohydrate determination in biofluids and semisolid biotissues. Chem. Sci. 2016, 7, 1487-1495.
(25) Ye, Niru; Huang, Siming; Yang, Huangsheng; Wu, Tong; Tong, Linjing; Zhu, Fang; Chen, Guosheng*; Ouyang, Gangfeng. Hydrogen-Bonded Biohybrid Framework-Derived Highly Specific Nanozymes for Biomarker Sensing. Anal. Chem. 2021, 93, 13981-13989.
(26) Zhong, Ningyi; Gao, Rui; Shen, Yujian; Kou, Xiaoxue; Wu, Jiayi; Huang, Siming*; Chen, Guosheng*; Ouyang, Gangfeng. Enzymes-Encapsulated Defective Metal-Organic Framework Hydrogel Coupling with a Smartphone for a Portable Glucose Biosensor. Anal. Chem. 2022, 94, 14385–14393.
(27) Chen, Guosheng; Huang, Siming; Kou, Xiaoxue; Zhang, Jin’ge; Wang, Fuxin; Zhu, Fang*; Ouyang, Gangfeng*. Novel Magnetic Microprobe with Benzoboroxole-Modified Flexible Multisite Arm for High-Efficiency cis-Diol Biomolecule Detection. Anal. Chem.2018, 90, 3387-3394.
(28) Kou, Xiaoxue; Tong, Linjing; Shen, Yujian; Zhu, Wangshu; Yin, Li; Huang, Siming*; Zhu, Fang*; Chen, Guosheng*; Ouyang, Gangfeng. Smartphone-assisted robust enzymes@MOFs-based paper biosensor for point-of-care detection. Biosensors and Bioelectronics 2020, 156, 112095.
(29) Wu, Tong; Huang, Siming*; Yang, Huangsheng; Ye, Niru; Tong, Linjing; Chen, Guosheng*; Zhou, Quan*; Ouyang, Gangfeng. Bimetal Biomimetic Engineering Utilizing Metal–Organic Frameworks for Superoxide Dismutase Mimic. ACS Materials Lett., 2022, 4, 4,751-757.
(30) Yang, Huangsheng; Fu, Jiahui; Huang, Wei; Huang, Wu,Tong; Huang, Siming; Chen, Guosheng*; Ouyang, Gangfeng. Self-Propelled, High-Crystalline Hydrogen-Bonded Enzymatic Framework Assembled by Bottom-Up Strategy. Small Structure 2023, 2200346.
(31) Gao. Rui; Zhong, Niyi; Tong, Linjing; Kou, Xiaoxue; Huang, Wei; Yang, Huangsheng; Huang Siming*; Wu, Jiayi; Chen, Guosheng*; Ouyang, Gangfeng. Mechanochemistry-guided reticular assembly for stabilizing enzymes with covalent organic frameworks. Cell. Rep. Phys. Sci. 2022, 3, 101153.
(32) Gao, Rui; Ye, Niru; Kou, Xiaoxue; Shen, Yujian; Yang, Huangsheng; Wu, Tong; Huang, Siming*; Chen, Guosheng*; Ouyang, Gangfeng. Hierarchically mesoporous Ce-based MOFs with enhanced alkaline phosphatase-like activity for phosphorylated biomarker sensing. Chem. Commun. 2022, 58, 12720-12723 (HOT paper).
(33) Huang, Hao; Kou, Xiaoxue; Gao, Rui*; Huang, Siming; Chen, Guosheng*; Ouyang, Gangfeng. Enzyme-Immobilized Porous Crystals for Environmental Applications. Environ. Sci. Technol. 2024, 58, 27, 11869–11886.
